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Hirozo Goto Selected Research

keishibukuryogan

1/2012Effect of keishibukuryogan on endothelial function in patients with at least one component of the diagnostic criteria for metabolic syndrome: a controlled clinical trial with crossover design.
1/2011Keishibukuryogan reduces renal injury in the early stage of renal failure in the remnant kidney model.
3/2010The traditional Japanese formula keishibukuryogan reduces liver injury and inflammation in patients with nonalcoholic fatty liver disease.
12/2008A Proteomic Approach for the Diagnosis of 'Oketsu' (blood stasis), a Pathophysiologic Concept of Japanese Traditional (Kampo) Medicine.
4/2008Keishibukuryogan ameliorates glucose intolerance and hyperlipidemia in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
10/2007Identification of a predictive biomarker for the beneficial effect of a Kampo (Japanese traditional) medicine keishibukuryogan in rheumatoid arthritis patients.
6/2007Effects of keishibukuryogan on vascular function in adjuvant-induced arthritis rats.
3/2007Protective effects of keishibukuryogan on the kidney of spontaneously diabetic WBN/Kob rats.
9/2006Keishibukuryogan (gui-zhi-fu-ling-wan), a Kampo formula, decreases disease activity and soluble vascular adhesion molecule-1 in patients with rheumatoid arthritis.
9/2002Keishi-bukuryo-gan preserves the endothelium dependent relaxation of thoracic aorta in cholesterol-fed rabbit by limiting superoxide generation.
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Hirozo Goto Research Topics

Disease

6Hypertension (High Blood Pressure)
01/2011 - 02/2003
5Stroke (Strokes)
01/2011 - 01/2003
4Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
12/2007 - 09/2004
4Hemolysis
02/2003 - 06/2002
3Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2012 - 01/2007
3Body Weight (Weight, Body)
03/2010 - 09/2005
3Rheumatoid Arthritis
12/2008 - 09/2006
3Diabetic Nephropathies (Diabetic Nephropathy)
09/2005 - 01/2003
2Hypoxia (Hypoxemia)
07/2014 - 01/2011
2Non-alcoholic Fatty Liver Disease
03/2010 - 03/2008
2Inflammation (Inflammations)
03/2010 - 09/2006
2Insulin Resistance
04/2008 - 01/2007
2Cough
09/2006 - 06/2006
2Atherosclerosis
09/2002 - 06/2002
1Human Influenza (Influenza)
01/2013
1Hyperemia
01/2012
1Skin Ulcer
01/2011
1Pressure Ulcer (Bedsore)
01/2011
1Fibrosis (Cirrhosis)
01/2011
1Renal Insufficiency (Renal Failure)
01/2011
1Chronic Kidney Failure (Chronic Renal Failure)
01/2011
1Glucose Intolerance
04/2008
1Type 2 Diabetes Mellitus (MODY)
04/2008
1Hyperlipidemias (Hyperlipidemia)
04/2008
1Alcoholic Fatty Liver
03/2008
1Liver Cirrhosis (Hepatic Cirrhosis)
03/2008
1Glioma (Gliomas)
12/2007
1Arthritis (Polyarthritis)
06/2007
1Hyperglycemia
03/2007
1Cataract (Cataracts)
09/2006
1Hypoglycemia (Reactive Hypoglycemia)
09/2006
1Diabetes Complications
09/2006
1Common Cold
09/2006
1Ischemia
09/2004
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
02/2003

Drug/Important Bio-Agent (IBA)

11keishibukuryoganIBA
01/2012 - 06/2002
4Blood Glucose (Blood Sugar)IBA
03/2007 - 06/2005
3Fibronectins (Fibronectin)IBA
01/2011 - 09/2005
3hachimijiogan (TJ 7)IBA
01/2011 - 06/2005
3CholesterolIBA
03/2010 - 06/2002
3Biomarkers (Surrogate Marker)IBA
10/2008 - 06/2005
3LipidsIBA
04/2008 - 01/2007
3Glucose (Dextrose)FDA LinkGeneric
04/2008 - 01/2007
3choto-sanIBA
12/2007 - 01/2003
3astaxanthine (astaxanthin)IBA
01/2007 - 01/2005
3Free RadicalsIBA
02/2003 - 06/2002
32,2'-azobis(2-amidinopropane) (ABAP)IBA
02/2003 - 06/2002
2Messenger RNA (mRNA)IBA
01/2011 - 12/2007
2Blood Proteins (Serum Proteins)IBA
10/2008 - 06/2005
2Antitussive Agents (Antitussives)FDA Link
09/2006 - 06/2006
2Citric Acid (Citrate)FDA LinkGeneric
09/2006 - 06/2006
2Antihypertensive Agents (Antihypertensives)IBA
03/2006 - 06/2005
2Proteins (Proteins, Gene)FDA Link
09/2005 - 06/2005
2SuspensionsIBA
02/2003 - 06/2002
1Biological FactorsIBA
07/2014
1juzentaihotoIBA
01/2013
1Fatty Acids (Saturated Fatty Acids)IBA
01/2012
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
01/2012
1Nonesterified Fatty Acids (NEFA)IBA
01/2012
1Malondialdehyde (Propanedial)IBA
01/2012
1toki-shakuyaku-sanIBA
01/2011
1CytokinesIBA
01/2011
1kamikihi-to (KKT)IBA
01/2011
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2011
1HaptoglobinsIBA
10/2008
1Verapamil (Calan)FDA LinkGeneric
10/2008
1L-Type Calcium Channels (Dihydropyridine Receptor)IBA
10/2008
1Insulin (Novolin)FDA Link
04/2008
1AdipokinesIBA
03/2008
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
12/2007
1Macrophage Colony-Stimulating FactorIBA
12/2007
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
12/2007
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2007
1AdiponectinIBA
01/2007
1Sorbitol (Yal)FDA Link
09/2006
1Aldehyde Reductase (Aldose Reductase)IBA
09/2006
1Galactose (Galactopyranose)FDA LinkGeneric
09/2006
1GalactitolIBA
09/2006
1PseudoephedrineFDA LinkGeneric
09/2006
1Nasal Decongestants (Decongestants)IBA
09/2006
1Codeine (Codeine Phosphate)FDA LinkGeneric
06/2006
1SolutionsIBA
06/2006
1Ephedrae herbaIBA
06/2006
1ElastinIBA
04/2006
1Transforming Growth Factor beta1 (TGF beta 1)IBA
09/2005
1Reactive Oxygen Species (Oxygen Radicals)IBA
06/2005
1IonsIBA
06/2005
1Adrenergic Receptors (Adrenergic Receptor)IBA
06/2005
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
01/2005
1Drinking WaterIBA
09/2004
1Neuroprotective AgentsIBA
09/2004
1oren gedoku toIBA
02/2003

Therapy/Procedure

12Kampo Medicine (Kampo)
01/2013 - 06/2002
3Oral Administration
04/2008 - 01/2003
2Lasers (Laser)
10/2008 - 06/2005
2Intraperitoneal Injections
09/2006 - 06/2006
1Therapeutics
01/2011
1Nephrectomy
01/2011
1East Asian Traditional Medicine (Oriental Medicine)
12/2007
1Traditional Medicine (Folk Remedies)
10/2007